Characteristic COVID-19 MIS-C
Mild, N = 2331 Moderate, N = 731 (Very) severe, N = 221 p-value2 Mild, N = 751 Moderate, N = 221 (Very) severe, N = 691 p-value2

Age

0.2 (0.1 - 3.4) 1.6 (0.3 - 11.3) 8.9 (0.6 - 13.8) <0.001 8.1 (5.1 - 11.5) 7.9 (6.5 - 13.0) 11.0 (9.0 - 13.5) <0.001

Gender

0.7 0.3

Male

126 (55%) 39 (53%) 10 (45%) 40 (56%) 13 (62%) 47 (69%)

Female

103 (45%) 34 (47%) 12 (55%) 32 (44%) 8 (38%) 21 (31%)

BMI (z-score) 3

-0.14 (-1.31 - 0.93) 0.43 (-0.82 - 1.29) -0.35 (-1.96 - 1.15) 0.4 0.11 (-0.81 - 0.81) -0.15 (-0.94 - 1.76) 0.40 (-0.59 - 1.44) 0.5

Hospital Admission

180 (81%) 71 (99%) 19 (100%) <0.001 64 (96%) 20 (100%) 68 (100%) 0.13

Length of Stay (d)

1 (1 - 2) 4 (3 - 8) 12 (6 - 42) <0.001 6 (4 - 7) 5 (3 - 9) 6 (4 - 8) 0.4

ICU admission

2 (1.1%) 1 (1.4%) 18 (95%) <0.001 0 (0%) 20 (100%) 68 (100%) <0.001

Length of Stay ICU (d)

4 (4 - 5) 3 (3 - 3) 7 (4 - 14) 0.2 2.0 (2.0 - 3.0) 4.0 (3.0 - 5.0) <0.001

Lymphocyte count available

0.2 0.2

Yes

111 (48%) 37 (51%) 15 (68%) 66 (88%) 16 (73%) 56 (81%)

No

122 (52%) 36 (49%) 7 (32%) 9 (12%) 6 (27%) 13 (19%)

Lymphopenia

63 (57%) 21 (57%) 11 (73%) 0.5 41 (62%) 8 (50%) 45 (80%) 0.025
3. Roede MJ & van Wieringen JC, bewerking TNO (1985) Growth diagrams 1980: Netherlands third nation-wide survey. Tijdschrift voor Sociale Gezondheidszorg, 63, 1-34.

1 Median (IQR); n (%)

2 Kruskal-Wallis rank sum test; Pearson's Chi-squared test