Characteristic COVID-19 MIS-C
Mild, N = 1131 Moderate, N = 371 (Very) severe, N = 81 p-value2 Mild, N = 431 Moderate, N = 161 (Very) severe, N = 341 p-value2

Age

0.4 (0.1 - 8.7) 8.1 (0.6 - 13.7) 12.5 (0.5 - 15.7) 0.036 9.9 (6.4 - 11.6) 10.0 (6.3 - 14.1) 11.3 (9.0 - 14.4) 0.061

Gender

0.8 0.13

Male

69 (62%) 22 (59%) 4 (50%) 21 (49%) 8 (50%) 24 (71%)

Female

43 (38%) 15 (41%) 4 (50%) 22 (51%) 8 (50%) 10 (29%)

BMI (z-score) 3

-0.09 (-0.96 - 1.04) 0.61 (-0.32 - 1.50) 0.92 (-0.86 - 1.73) 0.2 0.11 (-0.79 - 0.83) 0.44 (-0.27 - 1.96) 0.40 (-0.50 - 1.39) 0.5

Hospital Admission

84 (74%) 37 (100%) 8 (100%) <0.001 37 (88%) 16 (100%) 33 (100%) 0.046

Length of Stay (d)

1 (1 - 3) 4 (3 - 8) 20 (7 - 47) <0.001 5.00 (4.00 - 8.00) 5.00 (3.00 - 8.00) 7.00 (6.00 - 8.00) 0.2

ICU admission

2 (2.4%) 1 (2.8%) 7 (88%) <0.001 0 (0%) 16 (100%) 32 (97%) <0.001

Length of Stay ICU (d)

4 (4 - 5) 3 (3 - 3) 8 (4 - 24) 0.2 2.0 (2.0 - 3.2) 5.0 (3.0 - 6.0) <0.001

Lymphocyte count available

0.056 0.062

Yes

59 (52%) 25 (68%) 7 (88%) 39 (91%) 15 (94%) 25 (74%)

No

54 (48%) 12 (32%) 1 (12%) 4 (9.3%) 1 (6.2%) 9 (26%)

Lymphopenia

32 (54%) 16 (64%) 5 (71%) 0.5 21 (54%) 9 (60%) 18 (72%) 0.3
3. Roede MJ & van Wieringen JC, bewerking TNO (1985) Growth diagrams 1980: Netherlands third nation-wide survey. Tijdschrift voor Sociale Gezondheidszorg, 63, 1-34.

1 Median (IQR); n (%)

2 Kruskal-Wallis rank sum test; Pearson's Chi-squared test