Characteristic COVID-19 MIS-C
Mild, N = 1011 Moderate, N = 311 (Very) severe, N = 71 p-value2 Mild, N = 251 Moderate, N = 91 (Very) severe, N = 241 p-value2

Age

0.3 (0.1 - 8.1) 5.9 (0.6 - 13.5) 9.8 (0.4 - 16.0) 0.079 11.0 (8.5 - 12.2) 11.6 (6.3 - 14.4) 10.5 (9.0 - 15.0) 0.7

Gender

>0.9 0.9

Male

61 (61%) 20 (65%) 4 (57%) 15 (60%) 6 (67%) 13 (57%)

Female

39 (39%) 11 (35%) 3 (43%) 10 (40%) 3 (33%) 10 (43%)

BMI (z-score) 3

0.08 (-0.82 - 1.07) 0.51 (-0.32 - 1.49) 0.81 (-1.41 - 1.04) 0.6 0.03 (-0.87 - 0.73) -0.22 (-0.56 - 1.25) 0.69 (0.36 - 1.79) 0.2

Hospital Admission

75 (74%) 31 (100%) 7 (100%) 0.002 25 (100%) 9 (100%) 24 (100%)

Length of Stay (d)

2 (1 - 3) 4 (2 - 6) 21 (6 - 52) <0.001 6.5 (4.0 - 8.0) 6.0 (4.0 - 7.0) 7.0 (6.0 - 8.2) 0.2

ICU admission

2 (2.7%) 1 (3.2%) 6 (86%) <0.001 0 (0%) 9 (100%) 23 (96%) <0.001

Length of Stay ICU (d)

4 (4 - 5) 3 (3 - 3) 9 (6 - 30) 0.2 2.0 (2.0 - 3.0) 5.0 (3.5 - 6.5) 0.002

Lymphocyte count available

0.080 0.2

Yes

52 (51%) 21 (68%) 6 (86%) 22 (88%) 9 (100%) 18 (75%)

No

49 (49%) 10 (32%) 1 (14%) 3 (12%) 0 (0%) 6 (25%)

Lymphopenia

25 (48%) 12 (57%) 5 (83%) 0.2 12 (55%) 5 (56%) 10 (56%) >0.9

1 Median (IQR); n (%)

2 Kruskal-Wallis rank sum test; Pearson's Chi-squared test